Different Individuals Can Have Different Numbers of Functional V Gene $\kappa$

question 20

Multiple Choice

Different individuals can have different numbers of functional V gene segments as well as different numbers of constant region genes. This type of genetic polymorphism between individuals indicates that:

• A) The antibody heavy and light chain loci undergo more frequent mutation than other genes in the genome.
• B) The recombination machinery is active in germ cells.
• C) Individuals only need \(\kappa\) or \(\lambda\) light chains, but not both.
• D) The precise number of antibody gene segments in an individual is not important.
• E) Antibody gene segments underwent more frequent duplication during evolution than other genes in the genome.

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