The Cellular Distribution of MHC Class I Versus MHC Class

question 20

Multiple Choice

The cellular distribution of MHC class I versus MHC class II molecules is quite different, with MHC class II molecules generally expressed on a very limited set of cell types. This is because:

• A) It would be detrimental to have CD8 T cells killing macrophages or B cells.
• B) CD4 T cells generally secrete cytokines that act on macrophages and B cells.
• C) Viruses generally do not infect and replicate in macrophages and B cells.
• D) Dendritic cells are more important in stimulating CD4 than CD8 T cell responses.
• E) CD4 T cells can only kill macrophages, dendritic cells, and B cells.

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