In A $\rho$ -Independent Terminator, There Is a Palindrome Rich in G

question 38

Essay

In a $\rho$ -independent terminator, there is a palindrome rich in G $\equiv$ C base pairs, followed by 8-10 uridine residues. Explain how each of the following changes might affect terminator function: (a) substitution of cytidines for the 8-10 uridines; (b) mutations in the palindrome that decrease its G $\equiv$ C content; (c) elimination of half of the palindromic sequence.

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