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The Kinase LKB1 (Par4) Was First Identified in C

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Essay

The kinase LKB1 (Par4) was first identified in C. elegans as a factor required for asymmetric cell division/fate in the early embryo: PAR4 mutant cells divide symmetrically, resulting in early lethality. If the role of Par4 is similar in both contexts, what might you expect to observe by staining early C. elegans embryos with an antibody to this protein?


Definitions:

Variable Costing

A costing method that includes only variable production costs (direct labor, direct materials, and variable manufacturing overhead) in product costs.

Absorption Costing

Accounting method that includes all manufacturing costs (direct costs, variable and fixed overhead) in the cost of a product.

Variable Costing

A method of costing that includes only variable production costs in product costs, treating fixed manufacturing overhead as a period cost to be charged against revenue in the period incurred.

Absorption Costing

A strategy in accounting that involves incorporating costs related to manufacturing, including direct materials, direct labor, and variable and fixed overheads, into the price point of a product.

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