Once Expressed on the Surface of Host Cells, an MHC

question 10

Multiple Choice

Once expressed on the surface of host cells, an MHC protein remains stably associated with its bound peptide for several days. This highly stable peptide binding behavior is important because:

• A) It prevents peptide exchanges on the cell surface, ensuring that peptide:MHC complexes are reliable indicators of the proteins present inside that host cell.
• B) If the MHC protein lost its peptide it would become unstable, and would be rapidly internalized and degraded.
• C) Pathogens would otherwise evade the immune response by making decoy peptides that mimic host cell peptides.
• D) Pathogens would be able to evade the T cell response by making proteases that cleave MHC proteins inducing peptide release.
• E) Immune responses to infection often induce noxious chemicals that damage surface MHC proteins, and might result in peptide loss.

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Definitions:

Interactional Justice

The quality of the interpersonal treatment people receive when procedures are implemented, emphasizing respect and dignity.

Outcome Fairness

The perception among individuals that the outcomes of a decision or process are just, equitable, and appropriate.

Outcome Fairness

The perception that the results of a decision or process are distributed equitably among stakeholders.

Procedural Justice

The fairness and transparency of the processes that lead to outcomes or decisions, impacting the perceived legitimacy and acceptance of those decisions.